Histone-like protein a hlpa
WebIn lower eukaryotes, linker histone-like proteins can be found. In Tetrahymena, H1 molecules are similar to the CTD of metazoan H1 without a globular domain [34]. In Saccharomyces cerevisiae, the linker histone-like protein Hho1p possesses two globular domains [35], whereas S. pombe seems to lack a linker histone [36]. Webhistone, any of a group of simple alkaline proteins usually occurring in cell nuclei, combined ionically with DNA (deoxyribonucleic acid) to form nucleoproteins (q.v.). A unit …
Histone-like protein a hlpa
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WebHistone-like proteins (HLPs) are small and basic bacterial proteins that are associated with a nucleoid and play roles in maintaining DNA architecture and regulating DNA transactions such as replication, recombination/repair and transcription. The studies on HLPs from a variety of bacterial species … WebOct 1, 1997 · The HlpA protein mediates the joining of distant recombination sites into a complex nucleoprotein structure, as judged by beta-mediated site-specific recombination. The results presented provide evidence that HlpA is a functional plastid equivalent of nuclear and mitochondrial HMG1-like proteins and bacterial HU proteins.
WebHistone deacetylase (HDAC) inhibitors promote cell maturation, differentiation, and apoptosis through changes in gene expression. Differentiated epithelial cel WebOct 1, 2024 · To enhance the binding of the probiotics to the tumours, Ho et al. engineered E. coli Nissle 1917 to express histone-like protein A (HlpA) from Streptococcus …
WebApr 30, 2024 · The most effective and established method for altering microbiota compositions are antibiotics, which are often a first-line treatment for bacterial infections. 11 Antibiotics have prevented countless deaths and are mainstays in clinical care. However, instances of antibiotic use have recently been linked to negative clinical outcomes. Weblike factor) is essential for red blood cell maturation, whereas KLF4/GKLF (gut Kruppel-like factor) regulates the differen-tiation and maturation of dermal and gastrointestinal epithe-lial cells (15, 24, 26, 28). Furthermore, an emerging literature also supports a role for this family of transcriptional factors in vascular cell biology (7).
WebJul 25, 2024 · An exciting approach to colorectal cancer chemoprevention was recently detailed in which EcN was engineered to express histone-like protein A (HlpA) on the cell surface, allowing it to bind to cancer cells with upregulated heparan sulfate proteoglycan (HSPG) on their cell surface ( Ho et al., 2024 ).
WebCisplatin mediates the increased expression of the trimethylated form of histone H3 protein at the 27th amino acid (lysine) (H3K27me3) in the kidney cells. ... Disruptor of telomeric silencing 1-like (DOT1L) protein is the methyltransferase of H3K79. 35 It regulates cell cycle and cell senescence, 36,37 and increases the expression of the ... hache baiabrad smith \u0026 kathy surace-smithWebKeywords; HU-like protein; structure-specific DNA binding; chromatin-associated protein; plastid pro- tein. DNA in living cells is complexed with chromosomal pro- teins such as histones, histone-like and non-histone proteins that tightly pack the DNA as chromatin. In the nucleus of eukaryotes, DNA is wrapped around basic histone cores to form ... brad smith unionizationWebJun 1, 2007 · STREPTOCOCCAL HISTONE-LIKE PROTEINS. Bacterial histone-like proteins (HlpA) of streptococci may contribute to the virulence of infections by promoting monocytes/macrophages to synthesize and release proinflammatory cytokines. 113 HlpA are highly cationic and selective binding of HlpA to proteoglycans in the rabbit … hache avionWebSep 20, 2007 · Streptococcus intermedius is a commensal associated with serious, deep-seated purulent infections in major organs, such as the brain and liver. Histone-like DNA … brad smith uclaWebWhereas histone variant exchange implies a replacement of a canonical histone with a variant, histone turnover involves the replacement of older histone proteins with … hache a talonWebDec 2, 2024 · Spiruchostatin A, also known as OBP801, YM753, is a potent HDAC inhibitor with an IC 50 value of 2 nM. It (3-100 nM, 12 or 24 h) can induce apoptosis in a dose-dependent manner in U937 cells and induce apoptosis in human myelomonocytic lymphoma cells in a time- and dose-dependent manner. Among them, Spiruchostatin A can … brad smith united country