WebJun 7, 2024 · The purpose of the CompassHER2 pCR study (also known as EA1181), led by Nadine Tung, MD (pictured) of Beth Israel Deaconess Medical Center, is to find out if some patients with early-stage HER2 positive breast cancer can safely be treated with less chemotherapy than is generally used. Currently, these patients receive limited … WebThe COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease …
Site for EA1181 (CompassHER2-pCR): Preoperative THP and …
WebAug 18, 2024 · Overall, treatment outcomes were comparable, with 67% and 68% of the patients achieving a pCR with FEC-TCb-HP and TCb-HP, respectively. 30 Additionally, after a median follow-up of 48 months, event-free survival and OS were very similar in both arms, with 93.5% event-free survival rate in the TCb-HP arm compared with 92.7% in the … WebSite for EA1181 (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response Brief description of study The purpose of … stax theme
EA1181 (CompassHER2-pCR): Preoperative THP and postoperative …
WebFeb 11, 2024 · SWOG clinical trial number. CTSU/EA1181. (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response. Part 1 Component of: The CompassHER2 Trials (COMprehensive use of Pathologic response ASSessment to optimize therapy in HER2-positive breast cancer) … WebJul 2, 2024 · Ongoing clinical trials are testing this strategy (CompassHER2-pCR: NCT04266249). pCR also provides an opportunity to assess de-escalation of locoregional therapies. Currently, for patients with residual disease in the lymph nodes (ypN+), radiation therapy entails coverage of the undissected axilla, and may include supra/infraclavicular ... WebMay 10, 2024 · The CompassHER2-pCR trial (NCT04266249) is ongoing and will determine recurrence-free survival among patients with HER2+ breast cancer who receive an abbreviated neoadjuvant regimen and... stax thumb splint